Relief may be on the way for kids who tremble at the thought of another needle jab. One day the flu vaccine may simply be placed under the tongue.
Korean researchers say two doses of influenza vaccine under the tongue of mice primed the animals' immune system to fight off what would otherwise have been a deadly dose of flu.
Researchers say placing a couple of drops of liquid under the tongue gets the vaccine directly to mucus membranes and prompts a response both in mucus tissues throughout the body as well as in the immune system itself.
Next, they are turning their attention to people to see if the under-the-tongue vaccine also prompts a strong immune response in humans.
The findings appeared in Monday's online edition of Proceedings of the National Academy of Sciences.