Pakistani opposition leader Benazir Bhutto has been assassinated after a speech to thousands of supporters at a rally.

A party security adviser says Bhutto was shot in the neck and chest as she got into her vehicle, and then the gunman blew himself up.

Supporters learning the news have been smashing glass doors at the hospital where she died.

Some have been voicing their anger at Pakistan's president Pervez Musharraf. Others have been weeping.

Bhutto had twice served as Pakistan's prime minister. She returned in October from an eight-year exile.