Virginia retailers near the West Virginia line that sell cigarettes can expect to see sales go up.
West Virginia's cigarette tax increase goes into effect Thursday. The Mountain State is tacking on an extra 38 cents per pack, for a total of 55 cents.
Businesses along the West Virginia border are worried about losing revenue to neighboring states.
Ohio also has a 55-cent cigarette tax. Kentucky's is three cents, while Virginia's is the lowest in the country at two cents, though Virginia communities can set higher taxes.
West Virginia Governor Bob Wise sought the 38-cent increase to raise an annual $60 million for the state's Medicaid program, which provides health care to low-income and disabled residents.