Vladimir Guerrero homered and drove in four runs, Garret Anderson had three hits and two RBIs, and the Los Angeles Angels beat the Baltimore Orioles 9-4 on Wednesday.

Ervin Santana (13-5) allowed four runs and eight hits over seven innings with seven strikeouts and no walks. The first-time All-Star got as much run support in this outing as he did over his previous four starts combined, including a 5-2 loss at Camden Yards on July 27.