The Buffalo Bills will play the Washington Commanders at FedExField on Sunday, September 24 at 1:00 PM ET. Our computer model predicts the Bills will earn a victory -- keep scrolling for a full breakdown regarding the spread, over/under and final score.

The Bills surged on both sides of the ball last season, ranking second-best in scoring offense (28.4 points per game) and second-best in scoring defense (17.9 points allowed per game). On offense, the Commanders ranked 24th in the NFL with 18.9 points per game last season. Meanwhile, they ranked seventh in points allowed (304.6 points allowed per contest).

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Commanders vs. Bills Predictions and Picks

ATS Over/Under Score Prediction
Toss Up (Spread: Bills by 5.5) Over (44) Bills 27, Commanders 21

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Commanders Betting Info

  • Bookmakers have implied with the moneyline set for this matchup that the Commanders have a 33.3% chance to win.
  • Washington put together an 8-8-1 ATS record last season.
  • The Commanders covered the spread twice last season (2-2 ATS) when playing as at least 5.5-point underdogs.
  • Last year, five Washington games went over the point total.
  • The over/under for this game is 2.2 points higher than the average scoring total for Commanders games last season (41.8).

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Bills Betting Info

  • Based on this contest's moneyline, the Bills' implied win probability is 71.4%.
  • Buffalo won seven games against the spread last season, failing to cover eight times.
  • The Bills were favored by 5.5 points or more 13 times last season, and covered the spread in five of those contests.
  • Buffalo and its opponent combined to hit the over in six of 16 contests last season.
  • The point total average for Bills games last season was 47.7, 3.7 more points than the over/under for this matchup.

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Commanders vs. Bills 2022 Scoring Insights

Pts Pts Allowed Home Pts Home Pts Allowed Away Pts Away Pts Allowed
Buffalo 28.4 17.9 31.8 18.4 25.1 17.4
Washington 18.9 20.2 17.8 19 20.1 21.5

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